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500mg tablets of Depakote extended-launch Valproate or valproic acid is utilised primarily to treat epilepsy and bipolar problem and to forestall migraine problems.[21]

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There exists a heightened threat of valproate-induced acute liver failure and resultant deaths in sufferers with hereditary neurometabolic syndromes attributable to DNA mutations in the mitochondrial DNA Polymerase γ (POLG) gene (e.g. Alpers Huttenlocher Syndrome). Depakote is contraindicated in individuals recognized to possess mitochondrial disorders caused by POLG mutations and youngsters underneath two several years of age who're clinically suspected of getting a mitochondrial dysfunction [see CONTRAINDICATIONS].

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Normally clients begin at a small dose of medication as well as the dose is increased slowly but surely in excess of a number of months.

We anticipate reposting the pictures after we have been ready detect and filter out images that don't match the information delivered within the drug labels. NDC Codes

Depakote ER tablets and Depakote delayed-release tablets will also be made use of to prevent migraine headaches.

Connect with your healthcare supplier at once For those who have any with the symptoms detailed under. Your Health care supplier may do more exams right before and during your procedure with DEPAKOTE.

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It is very important to tell your doctor how you feel matters are likely over the initially number of weeks following you check here start having valproate. It will most likely take many months to find out sufficiently big adjustments as part of your signs and symptoms to make your mind up if valproate is the proper medication in your case.

Patients with Mitochondrial Illness: There is certainly a heightened chance of valproate-induced acute liver failure and resultant deaths in clients with hereditary neurometabolic syndromes a result of DNA mutations of your mitochondrial DNA Polymerase γ (POLG) gene (e.g. Alpers Huttenlocher Syndrome). Depakote is contraindicated in people recognised to have mitochondrial disorders caused by POLG mutations and youngsters less than two years of age that are clinically suspected of having a mitochondrial condition [see Contraindications (4)].

are Expecting or may turn into Expecting. DEPAKOTE might damage your unborn toddler. See “2. Depakote could damage your unborn baby” over To learn more.

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